Trauma can also cause liver dysfunction – Sohu health-truffe

Trauma can cause abnormal liver function – health Sohu today received a manuscript "Adverse Drug Reactions Journal" asked me to review the manuscript, introduces a case of right lower extremity fractures in patients with severe trauma using cefathiamidin anti infection treatment, 4 hours after the onset of liver function abnormal, the doctor linked to antibiotics for submission to the "adverse reaction of Adverse Drug Reactions Journal". After reading this manuscript, I felt that the patient had obvious liver injury after 4 hours of medication, alanine aminotransferase increased to 364 U L, accompanied by a significant increase in creatine kinase, CK 972 U L. It is believed that the time from drug use to liver injury is too short. What is the cause of liver damage? According to the author of the report, they were the patients with hepatitis B, hepatitis C, hepatitis and hepatitis viral markers were examined, excluding caused by viral infection, but not the other patients may lead to liver injury history. What are the reasons? Acute trauma can lead to abnormal liver function? With this question, I searched the medical literature. Indeed, the harvest: trauma can also cause abnormal liver function. Acute severe trauma can lead to systemic inflammatory response, inflammatory substances in the liver, can lead to liver damage. Moreover, some enzymes in liver cells also exist in muscles, bones, such as alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, creatine kinase, muscle injury will certainly lead to these enzymes increased in blood, which showed abnormal liver function. Therefore, I think the liver injury in this patient is likely to be related to trauma. The purpose of this blog is to tell you that there are many reasons leading to abnormal liver function, liver function abnormalities should be carefully looking for reasons, so as to avoid misdiagnosis. Reference: [1] Cui Shuyan. Clinical analysis of changes of liver function after trauma. The study of trace elements and health. 2016 (01): 90-91. [2], Wang Ke, Wang Zhenhao, Wang Quanchu, Wang Lifeng. Fracture trauma caused by abnormal liver function analysis. People’s military. 2009 (11): 745-746. [3] King Chu, Yao Yongming. Research progress of liver function damage trauma. People’s military. 2009 (11): 743-744. [4] Yin Ying, Lan Yu, Sun Chengdong. Analysis of influencing factors of 105 cases of liver injury after trauma. Beijing medicine. 2008 (03): 133-136. [5] Yin Ying, Lan Yu, Sun Cheng building. The changes of liver function after trauma and its clinical significance. World Journal of Gastroenterology. 2008 (02): 217-220. [6] money what cloth, Zheng Zhiqun. Risk factors and preventive strategy of acute liver damage after severe trauma. Journal of Third Military Medical University 2006 (16. 1729-1730. [7] Yang Feng, Zhou Zeqiang. Early post trauma相关的主题文章:

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